Editorial for Revista Portuguesa de Oncologia, issue 4, 2025
As we bring to a close the fourth and final issue of the Revista Portuguesa de Oncologia (RPO) for this year, a brief reflection is warranted on the recent trajectory of this publication, which is increasingly and consistently affirming itself as an active and representative voice of the national oncology community. The year 2025 witnessed […]
Highlights from the 2025 ASCO annual meeting: gynecologic cancer
TRUST: Trial of Radical Upfront Surgical Therapy in Advanced Ovarian Cancer (ENGOT-ov33/AGO-OVAR OP7) O TRUST foi um ensaio randomizado que comparou a melhor estratégia de tratamento cirúrgico em mulheres com carcinoma epitelial do ovário avançado (IIIB-IVB) recentemente diagnosticado, desde que a doença fosse considerada ressecável. Quase 800 mulheres elegíveis foram randomizadas numa proporção de 1:1 […]
Evolving paradigms in digestive oncology: highlights and reflections from ASCO 2025
Trastuzumab deruxtecan (T-DXd) versus ramucirumab (RAM) + paclitaxel (PTX) in second-line treatment of patients (pts) with human epidermal growth factor receptor 2-positive (HER2+) unresectable/metastatic gastric cancer (GC) or gastroesophageal junction adenocarcinoma (GEJA): primary analysis of the randomized, phase 3 DESTINY-Gastric04 (DG04) study DG04, which evaluated T-DXd against the current standard of care combination of RAM […]
Personalised nutritional care in an integrated screening protocol: the green way of oncology nutrition in Portugal
Introduction Nutrition is critical to the management of cancer, and it is of utmost importance to identify clinical findings that may negatively impact tolerance to treatments, quality of life, and survival, e.g. malnutrition, sarcopenia (weight loss and depletion of muscle mass and function), physical function or cachexia (severe weight loss characterised by a persistent decline […]
Definition of therapeutic limits and do-not-resuscitate decision in Oncology: the perception of different healthcare professionals in a portuguese hospital
Introduction The definition of therapeutic limits and the establishment of do-not-resuscitate decisions are complex decisions that involve multidimensional assessments and the consideration of individual, prognostic, and ethical factors1,2. In cancer patients, they are often necessary in advanced stages of the disease, in the absence of therapeutic options, and in situations with a prognosis of short-term […]
Pneumocystis jirovecii pneumonia during adjuvant chemotherapy of breast cancer: a hidden complication of the prophylactic corticosteroids?
Introduction Breast cancer remains the leading cause of cancer-related death among women in Europe1, despite recent declines in mortality rates. Over the last 5 years, most European countries have reported significant reductions in breast cancer mortality2, mainly attributed to advances in systemic treatment and, to a lesser extent, improvement in screening and diagnostic methods. Neoadjuvant […]