Editorial for Revista Portuguesa de Oncologia, issue 4, 2025
Highlights from the 2025 ASCO annual meeting: gynecologic cancer
Evolving paradigms in digestive oncology: highlights and reflections from ASCO 2025
Personalised nutritional care in an integrated screening protocol: the green way of oncology nutrition in Portugal
Definition of therapeutic limits and do-not-resuscitate decision in Oncology: the perception of different healthcare professionals in a portuguese hospital
Pneumocystis jirovecii pneumonia during adjuvant chemotherapy of breast cancer: a hidden complication of the prophylactic corticosteroids?
Highlights from the 2025 American Society of Clinical Oncology Annual meeting: head-and-neck cancers
Introduction Head and neck squamous cell carcinoma (HNSCC) represents a heterogenous group of diseases, and remains a major global health challenge, with survival rates for locally advanced disease showing limited improvement despite multimodal therapy strategies. The American Society of Clinical Oncology (ASCO) Annual Meeting is a premier global forum for presenting cutting-edge oncology research and […]
Molecularly targeted agents and tumor biology
Regarding the area of “Developmental Therapeutics Molecularly Targeted Agents and Tumor Biology,” the presentations selected were: – Abstract 3002 – Phase I study of iza-bren (BL-B01D1), an epidermal growth factor receptor × human epidermal growth factor receptor 3 (EGFR × HER3) bispecific antibody-drug conjugate (ADC), in patients (pts) with locally advanced or metastatic small cell […]
Highlights from the 2025 ASCO annual meeting: central nervous system
Stereotactic radiation versus hippocampal avoidance whole brain radiation in patients with 5-20 brain metastases: A multicenter, phase 3 randomized trial Prior trials have demonstrated that stereotactic radiosurgery (SRS)/stereotactic radiotherapy (SRT) yields better outcomes than traditional whole brain radiotherapy (WBRT) in patients with 1-4 brain metastases, and that hippocampal avoidance WBRT (HA-WBRT) is superior to traditional […]
Breast cancer panel: summary of 5 key studies
At the Best of ASCO 2025 meeting hosted by the Portuguese Society of Oncology, five studies were presented in the Breast Cancer panel, all considered relevant to present clinical practice. One focused on early-stage breast cancer (NeoCARHP), while the remaining studies addressed advanced breast cancer (aBC), including two on luminal human epidermal growth factor receptor […]
